A huge elevation in the Michaelis-Menten parameters (aKm, avm) of the human erythrocyte acetylcholine esterase (AChE.Ec.3.1.1.7) in splenomegally were obseIVed. 76 blood samples were assayed from the hospitalized patients compared with ltIe 'normal blood samples as control. Time course effect of the disease upto six months were also obseIVed. Attempts have been made to suggest possible interpretations for the change observed.
S F MABOOD ,Z M KHAN ,H ULLAH ,
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